You perform dna microarray experiments on cancer cells at, Ask an Expert

Academics

You perform DNA microarray experiments on cancer cells at different time points (0, 6, and 12 hours) following the addition of a novel anti-cancer drug. You obtain the following normalized and scaled microarray data for the genes Myc, p53, and Ras.

Gene Name 0 hr 6 hr 12 hr
Myc 1.0 0.2 -1.2
P53 -1.1 0.4 0.7
Ras 1.3 -1.4 0.1

a. Use the Euclidean distance method to find out the following distance matrix:
Gene Myc p53 Ras
Myc
P53
Ras

b. Which two genes would be clustered together ?rst using the hierarchical clustering method'?
c. If we are using the Complete Linkage cluster method, what is the new distance between the remaining (unclustered) gene and the new gene cluster generated in part (b)?

View complete question

Biology, Academics

Category:- Biology
Reference No.:- M925002

Have any Question?Write your Review or question?

Related Questions in Biology

How do i calculate the number of molecules needed for

How do I calculate the number of molecules needed for lethal dose? I am given the chemical name's LD50 and the "Estimated Lethal Dose (in grams) for 60kg human.

Assignment -the upper-case blue letters are the 14th exon

Assignment - The upper-case, blue letters are the 14th exon (of 20) in the Hephl1 gene in mice. The lower-case (black) letters are from the flanking introns. The highlighted bases indicate primers that may be used to ge ...

What is the process of turning polynucleotides into

What is the process of turning polynucleotides into proteins?

What is the phenotypic ratio for the offspring of a mother

What is the phenotypic ratio for the offspring of a mother who is homozygous dominant for blonde hair and a blonde-haired father who is heterozygous.

Question summaryfor readability please be sure to

Question: Summary For readability, please be sure to double-space your assignments. A new wild strain of nopal cactus has been identified as having remarkable promise to solve the international dietary manganese deficit ...

Describe the form of endocytosis that involves the movement

Describe the form of endocytosis that involves the movement of large amount of liquid into the cell.

Effect of light intensityfor the effect of light intensity

Effect of Light Intensity For the Effect of Light Intensity Experiment, calculate the rate of oxygen production for the light intensity of 6. Subtract the original volume at 00:00:00 from the final reading at 00:02:00 to ...

Question this is the final project of the case

Question: This is the final project of the case study 1. Identify the specific case study you chose and the tool(s) you would employ to analyze the healthcare environment. 2. Provide an explanation of how the selected to ...

In a cross between two heterozygous aa individuals what is

In a cross between two heterozygous (Aa) individuals, what is the likely percentage of the offspring that will be heterozygous

A man and woman both with normal vision have 1 a

A man and woman, both with normal vision, have (1) a color-blind son who has a daughter of normal vision; (2) a daughter of normal vision who has one color-blind son and one normal vision son, and (3) another daughter of ...

4,153,160 Questions Asked
13,132 Experts
2,558,936 Questions Answered

Ask Experts for help!!

Looking for Assignment Help?

Start excelling in your Courses, Get help with Assignment

Write us your full requirement for evaluation and you will receive response within 20 minutes turnaround time.

Ask Now Help with Problems, Get a Best Answer

Recent Questions

Ask Biology Expert