Ask Question, Ask an Expert

+1-415-315-9853

info@mywordsolution.com

Ask Biology Expert

You are interested in cell size regulation and discover that signaling through an enzyme-coupled receptor is important for the growth (enlargement) of mouse liver cells. Activation of the receptor activates adenylyl cyclase, which ultimately leads to the activation of PKA, which then phosphorylates a transcription factor called TFS on threonine 42. This phosphorylation is necessary for the binding of TFS to its specific sites on DNA, where it then activates the transcription of Sze2, a gene that encodes a protein important for liver cell growth. You find that liver cells lacking the receptor are 15% smaller than normal cells, whereas cells that express a constitutively activated version of PKA are 15% larger than normal liver cells. Given these results, predict whether you would expect the cell's size to be bigger or smaller than normal cells if cells were treated in the following fashion.

A. You create a version of the receptor that is constitutively active.

B. You add a drug that inhibits adenylyl cyclase.

Biology, Academics

  • Category:- Biology
  • Reference No.:- M943173

Have any Question? 


Related Questions in Biology

How do energy and nutrients move through ecosystems

How do energy and nutrients move through ecosystems? Indicate whether each is recycled. Define trophic levels and explain their involvement/role in energy movement.

Does every mutation that causes a nucleotide base change

Does every mutation that causes a nucleotide base change also cause a change in the amino acid sequence of a protein? Explain.

What policies at the local state or federal level eg

What policies at the local, state or federal level (e.g., education, transportation, employment, etc.) might reduce social and economic inequities? (b) What would a more equitable society look like? (c) Who can make it h ...

What are two ecosystems in the region where you live

What are two ecosystems in the region where you live (Southeastern US) where you live? What are some examples of intrinsic and instrumental values provided by the ecosystems?

Explain how the decline in genetic diversity with distance

Explain how the decline in genetic diversity with distance from Africa supports the Out of Africa hypotheses.

For this assignment you will select 4 fermented foods to

For this assignment, you will select 4 fermented foods to include in a full course dinner menu. Not every dish in the menu needs to be fermented, but 4 fermented products have to be included. The menu should have an appe ...

Annotated bibliographypick a type of cancer to research

Annotated Bibliography Pick a type of cancer to research. Find articles that answer questions concerning your chosen type of cancer. This assignment will help you to organize the sources you will use in the Unit V Resear ...

The end products of both mitosis and meiosis is a set of

The end products of both mitosis and meiosis is a set of chromosomes. Explain the differences between the two sets. Suppose that Mendel had decided to use dogs for his experiments. What problems would he have had that he ...

Urgent two immune system questionsactivated t-helper cells

URGENT: Two immune system questions: Activated T-helper cells aid in humoral immune responses by releasing cytokines which promote antibody production, phagocytosis, neutralization and apoptosis. Which parts of this stat ...

What is the process of dna replication please include

What is the process of DNA replication? Please include descriptions and possibly diagrams to further explain the process.

  • 4,153,160 Questions Asked
  • 13,132 Experts
  • 2,558,936 Questions Answered

Ask Experts for help!!

Looking for Assignment Help?

Start excelling in your Courses, Get help with Assignment

Write us your full requirement for evaluation and you will receive response within 20 minutes turnaround time.

Ask Now Help with Problems, Get a Best Answer

Section onea in an atwood machine suppose two objects of

SECTION ONE (a) In an Atwood Machine, suppose two objects of unequal mass are hung vertically over a frictionless

Part 1you work in hr for a company that operates a factory

Part 1: You work in HR for a company that operates a factory manufacturing fiberglass. There are several hundred empl

Details on advanced accounting paperthis paper is intended

DETAILS ON ADVANCED ACCOUNTING PAPER This paper is intended for students to apply the theoretical knowledge around ac

Create a provider database and related reports and queries

Create a provider database and related reports and queries to capture contact information for potential PC component pro

Describe what you learned about the impact of economic

Describe what you learned about the impact of economic, social, and demographic trends affecting the US labor environmen