Ask Question, Ask an Expert

+1-415-315-9853

info@mywordsolution.com

Ask Biology Expert

You are interested in cell size regulation and discover that signaling through an enzyme-coupled receptor is important for the growth (enlargement) of mouse liver cells. Activation of the receptor activates adenylyl cyclase, which ultimately leads to the activation of PKA, which then phosphorylates a transcription factor called TFS on threonine 42. This phosphorylation is necessary for the binding of TFS to its specific sites on DNA, where it then activates the transcription of Sze2, a gene that encodes a protein important for liver cell growth. You find that liver cells lacking the receptor are 15% smaller than normal cells, whereas cells that express a constitutively activated version of PKA are 15% larger than normal liver cells. Given these results, predict whether you would expect the cell's size to be bigger or smaller than normal cells if cells were treated in the following fashion.

A. You create a version of the receptor that is constitutively active.

B. You add a drug that inhibits adenylyl cyclase.

Biology, Academics

  • Category:- Biology
  • Reference No.:- M943173

Have any Question? 


Related Questions in Biology

Explain how stems cells are can be used to treat diseases

Explain how stems cells are can be used to treat diseases and injury, with special focus on spinal cord injuries.

Phylum arthropodathe earths largest phylum is arthropoda

Phylum Arthropoda The Earth's largest phylum is Arthropoda, including centipedes, millipedes, crustaceans, and insects. The insects have shown to be a particularly successful class within the phylum. What biological char ...

1which group of algae appears to be the most closely

1. Which group of algae appears to be the most closely related to the ancestors of true plants? Name one feature that appears to be homologous. 2. What are microphylls and which group of seedless vascular plants are they ...

1 how cando you reduce the amount of waste and pollution

1. How can/do YOU reduce the amount of waste and pollution that you create?  In other words, describe 3 things that you can do/already do to reduce, reuse and recycle more. 2. The City of Phoenix recently started a progr ...

Phylum arthropodathe earths largest phylum is arthropoda

Phylum Arthropoda The Earth's largest phylum is Arthropoda, including centipedes, millipedes, crustaceans, and insects. The insects have shown to be a particularly successful class within the phylum. What biological char ...

Focusing on thenbsprespiratory digestive urinary and

Focusing on the  respiratory, digestive, urinary, and reproductive systems.   Create a scenario  and give your patient a disease associated with any of these systems and present the history and symptoms of the particular ...

Lake stratificationhow does heat affect the tripariat

Lake Stratification: How does heat affect the tripariat thermal structure of a lake (epiliminion, thermocline and hypolimnion) during the summer and does the application of wind change this?

1 starting with the umbilical vein listchart the general

1) Starting with the umbilical vein, list/chart the general flow of blood through the fetus of a pig. 2) What special features of the lung make it a useful organ for gas exchange?

1 which type of vessels arteries or veins has more muscle

1) Which type of vessels, arteries, or veins, has more muscle fibers? What is the functional significance of this? 2) In general, we have no conscious control over smooth muscle or cardiac muscle function, whereas we can ...

Weve all had experiences where we have been frustrated by a

We've all had experiences where we have been frustrated by a decision that our supervisor made. You have probably blamed this decision on your boss being "closed-minded," "stubborn," or "pigheaded." But after reading the ...

  • 4,153,160 Questions Asked
  • 13,132 Experts
  • 2,558,936 Questions Answered

Ask Experts for help!!

Looking for Assignment Help?

Start excelling in your Courses, Get help with Assignment

Write us your full requirement for evaluation and you will receive response within 20 minutes turnaround time.

Ask Now Help with Problems, Get a Best Answer

WalMart Identification of theory and critical discussion

Drawing on the prescribed text and/or relevant academic literature, produce a paper which discusses the nature of group

Section onea in an atwood machine suppose two objects of

SECTION ONE (a) In an Atwood Machine, suppose two objects of unequal mass are hung vertically over a frictionless

Part 1you work in hr for a company that operates a factory

Part 1: You work in HR for a company that operates a factory manufacturing fiberglass. There are several hundred empl

Details on advanced accounting paperthis paper is intended

DETAILS ON ADVANCED ACCOUNTING PAPER This paper is intended for students to apply the theoretical knowledge around ac

Create a provider database and related reports and queries

Create a provider database and related reports and queries to capture contact information for potential PC component pro