Ask Question, Ask an Expert

+1-415-315-9853

info@mywordsolution.com

Ask Biology Expert

You are interested in cell size regulation and discover that signaling through an enzyme-coupled receptor is important for the growth (enlargement) of mouse liver cells. Activation of the receptor activates adenylyl cyclase, which ultimately leads to the activation of PKA, which then phosphorylates a transcription factor called TFS on threonine 42. This phosphorylation is necessary for the binding of TFS to its specific sites on DNA, where it then activates the transcription of Sze2, a gene that encodes a protein important for liver cell growth. You find that liver cells lacking the receptor are 15% smaller than normal cells, whereas cells that express a constitutively activated version of PKA are 15% larger than normal liver cells. Given these results, predict whether you would expect the cell's size to be bigger or smaller than normal cells if cells were treated in the following fashion.

A. You create a version of the receptor that is constitutively active.

B. You add a drug that inhibits adenylyl cyclase.

Biology, Academics

  • Category:- Biology
  • Reference No.:- M943173

Have any Question? 


Related Questions in Biology

What is the difference between prokaryotes and

What is the difference between prokaryotes and eukaryotes?

1 starting with the umbilical vein listchart the general

1) Starting with the umbilical vein, list/chart the general flow of blood through the fetus of a pig. 2) What special features of the lung make it a useful organ for gas exchange?

1 starting with the umbilical vein listchart the general

1) Starting with the umbilical vein, list/chart the general flow of blood through the fetus of a pig. 2) What special features of the lung make it a useful organ for gas exchange?

Assume the role of a research scientist who is applying for

Assume the role of a research scientist who is applying for grant money to fund research on ALS. Describe the particular area of research that you would investigate (drug-based therapies that would slow the progression o ...

Discussion topictopic 1 invasive or alien speciesinvasive

Discussion Topic Topic #1 Invasive or Alien Species Invasive or alien species have decimated natural ecosystems and cost us untold millions of dollars in environmental damage. Define what constitutes an invasive  or alie ...

What is the role of abiotic factors in an ecosystem in

What is the role of abiotic factors in an ecosystem? In other words, how do they affect food webs? Why is it easier to classify protists by methods of nutrition and movement than by habitat (where they live)? Briefly exp ...

You believe that the cytosolic protein p007 is involved in

You believe that the cytosolic protein p007 is involved in mediating growth hormone-stimulated proliferation in cells. You wish to establish a cell model using your cultured fibroblasts. Provide clear explanations to the ...

Topic systemic pathophysiology of the respiratory and

Topic: Systemic Pathophysiology of the Respiratory and Gastrointestinal Systems Objective: Discuss a disease, condition or syndrome affecting the cardiovascular system and current research, events, or interesting facts a ...

Please describe four different categories of tissue

Please describe four different categories of tissue engineering strategies for repairing bone and cartilage injuries separately, and compare the advantages and disadvantages of these strategies?

1 explain the normal hormonal control of male sexual

1) Explain the normal hormonal control of male sexual development by the hypothalamus pituitary-gonadal axis. 2) Are there other hormones that might influence reproductive maturation? Which ones and how do they affect gr ...

  • 4,153,160 Questions Asked
  • 13,132 Experts
  • 2,558,936 Questions Answered

Ask Experts for help!!

Looking for Assignment Help?

Start excelling in your Courses, Get help with Assignment

Write us your full requirement for evaluation and you will receive response within 20 minutes turnaround time.

Ask Now Help with Problems, Get a Best Answer

WalMart Identification of theory and critical discussion

Drawing on the prescribed text and/or relevant academic literature, produce a paper which discusses the nature of group

Section onea in an atwood machine suppose two objects of

SECTION ONE (a) In an Atwood Machine, suppose two objects of unequal mass are hung vertically over a frictionless

Part 1you work in hr for a company that operates a factory

Part 1: You work in HR for a company that operates a factory manufacturing fiberglass. There are several hundred empl

Details on advanced accounting paperthis paper is intended

DETAILS ON ADVANCED ACCOUNTING PAPER This paper is intended for students to apply the theoretical knowledge around ac

Create a provider database and related reports and queries

Create a provider database and related reports and queries to capture contact information for potential PC component pro