You are designing a novel antibiotic to combat a gram-negative bacterial infection. Based on what you know about other antibiotics for gram-negative bacterial infections, a possible mode of action for this antibiotic could be

1. An inhibitor of the activity of the proteins to which the carbohydrates of the cell wall are linked
2. A low molecular weight molecule with beta-lactamase activity
3. A compound previously developed as a ribosomal inhibitor of the steps in peptide bond formation in protein synthesis that would therefore block formation of all the non-sugar links in the cell wall.
4. A compound that inhibits the formation of isopeptide linkages or linkages involving D-amino acids.
5. An inhibitor of hyaluronic acid synthesis.