Why were Joseph's left face and hand paralyzed, but not the rest of his arm or his leg?

What is preventing Joseph from moving his left hand? In your answer, include the following:

First, describe normal function of a motor neuron that forms a synapse with a muscle cell. How is the signal that initiates movement transmitted from the neuron to the muscle? Describe this process in detail.

Next, keeping in mind that the motor neuron itself is not damaged, explain how damage or destruction of a neuron that communicates with the motor neuron prevents Joseph from moving his hand.

With time, and perhaps some physical therapy, Joseph may recover some of the movement in his left hand and face. What factors might

contribute to this recovery? In your answer, include the following:

Why can't Joseph's brain simply replace those neurons that were damaged and destroyed by the stroke?

How might compensation allow Joseph to regain some of his lost movement?

Describe at least one experimental treatment that might improve movement in Joseph's case, and explain how this treatment would impact Joseph's nervous system.