a. Why is it impossible to induce nonsense mutations (represented at the mRNA level by the triplets UAG, UAA, and UGA) by treating wild-type strains with mutagens that cause only A-T? G-C transitions in DNA?
b. Hydroxylamine (HA) causes only G-C ? A-T transitions in DNA. Will HA produce nonsense mutations in wild-type strains?
c. Will HA treatment revert nonsense mutations?