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Which enzyme acts on pyruvate in mitochondria and converts it to acetyl CoA?Name its components and cofactors associated with it.

Pyruvate dehydrogenase complex acts on pyruvate in mitochondria and converts it to acetyl CoA. Pyruvate dehydrogenase, dihydrolipoyl transacetylase and dihydrolipoyl dehydrogenase are its components. The cofactors associated with it are NAD, FAD, TDP, CoA and lipoic acid.

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