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a) What would be the effect on ATP production of adding a substance like 2,4-dinitrophenol(alprotonophore) that makes the mitochondrial membrane leaky to protons?

b) Suppose that the gulcose supply to the cell is gratly reduced. What would be the effect on CO2 procuction by the mitochondrion?

c)Pretend that you are playing mitochondrial CSI. You find that the mitochondria has been poisoned and it smells distincly of almonds... Cyanide! Cyanide (CN-) poisons the electron transport chain by interfering with cytochrome C oxidase. Explain what happends to the mitochondria when Cytochrome C oxidase is no longer able to function. (Hint: does it still form a prton gradient? why/how? Can it still make ATP? why/how?)

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