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  1. What is hyaline cartilage? Where is it found? Why is more of it found in growing children and adolescents than mature adults?
  2. Compare and contrast intramembranous and endochondral ossification in a developing baby(fetus). For which bones do these two types of ossification apply? How is the building of bone different for both of these processes?
  3. For endochondrial ossificaiton, where is the first ossification center located? The second?
  4.  Which bones display interstitial growth? interstitial growth is most like what form of ossification? Explain.
  5.  How are both osteoblasts and osteoclasts involved in appositional bone growth?
  6. Describe the different zones of growth at the epiphyseal plate. How does growth at the epiphyseal plate explain how children's bones grow long
  7. What is bone remodeling and what are the two processes that control bone remodeling? Why is exercise important for preventing problems like osteoporosis?
  8. Explain how various hormones can actually affect bone growth and remodeling.
  9. Apply your knowledge: Andre the Giant, well-known for his role in the movie The Princess Bride, was thought to have a condition referred to as "gigantism." This is caused by an abnormally high production of growth hormone. Explain how this could lead to Andre becoming a giant.
  10. Apply your knowledge: Achondroplastic dwarfism occurs when there is a mutation in the fibroblast growth factor gene (can be spontaneous or inherited) that causes abnormal growth of cartilage. This results in individuals with short stature and short limbs but yet their heads that relatively normal in size. Explain how this may occur knowing what you know about how bones develop.
  11. Explain why osteoporosis is more likely to happen in elderly women

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