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Throughout neural development, outgrowing nerve cell axons should interact with their cellular environment in order to find out correct organization and connectivity. Cell adhesion molecules (CAMs) are prominent one pass transmembrane glycoproteins which arbitrate the signalling essential to make sure correct targeting of these nerve axons.

How a cell adhesion transmembrane protein is translocated or sorted initially so that it will be interleaved in the plasma membrane as a type I membrane protein?

[Hint: Illustrate the specific steps which a type I transmembrane protein will go through in RER for insertion in the membrane].

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