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This assessment task requires you to work individually to apply your understanding of toxicology, to analyse a toxicological event/scenario and produce a technical report. This assignment is meant to assist you to consolidate your knowledge of toxicology in the context of a case study. It will require you to find toxicological information and to interpret according to principles that you have learned in this unit.

You are required to:

- choose one scenario (from those attached), and analyse the data/information provided;

- nominate the audience that the report is directed to;

- research current literature;

- create a professional written technical report, meeting industry standards for a professional audience; and

The elective topics and the core topics are to be used as sources of information and important toxicological principles.

It is important that you do not just state information - you must analyse/discuss/comment on data information you use and relate back to the specific scenario question or task - you are providing expert advice so need to analyse the information to provide advice to the stakeholder.

General Instructions

The final topics in this unit are designed to provide background information on a number of applied areas of toxicology. You need not study all of these but should use them to help you understand these professional areas and to consolidate your knowledge of toxicology.

For your final assignment, there are four case studies to choose from. You should select just one of these to complete. Whichever you chose, it will provide the same opportunity to bring together the basic principles of toxicology introduced throughout this unit and to learn how to apply this knowledge to a real world problem in a professional context.

Report

The assignment must be submitted as a report (2,000 words not including references) written for a specified audience and purpose (see the details in the relevant cases studies). Please read the specific instructions for each case study. The report should have the following section headings and relevant content.

- Your name and student number

- Case Study Title

- Abstract
Write a very short summary of your report

- Suspected toxic substance
Give the chemical and common name (if any) of the substance and CAS number
(CAS Registry Numbers are unique numerical identifiers assigned by the Chemical Abstracts Service to every chemical described in the open scientific literature).

- ADME
List the possible routes of uptake of this substance, the relevant metabolites if any, and the routes of excretion. Indicate the half-life (or lives) of the substance and relevant toxic metabolites in the body, and indicate if it can accumulate in the body.

- Toxicology of the suspected substance
Summarise the toxic effects of the substance, the target organs and the toxic mechanism. Give the acute and toxic doses (eg LD50, LC50, SHD, chronic toxic doses as relevant).
Indicate the time course of the effects - for example are they delayed and by how long.

- Conclusion
Does the information support the details in the case study or not

- Other Information
Provide specific information suitable for the specialist toxicologists relevant to the case study you chose (see the specific instructions for each case study).

- References

All information included in the report must be properly referenced. Any quotations must be identified in italics or quotation marks and the source included in the references.

Length - 2,000 words for the report

Attachment:- Case study.rar

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