There are two general mechanisms of mirnaago complexes. if, Ask an Expert

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There are two general mechanisms of miRNA/AGO complexes. If miRNAs are fully complementary with mRNAs, AGO can cleave these targets. If there are mismatches between the middle positions of miRNAs and their targets, then the miRNA/AGO complexes can bind mRNAs to execute translational inhibition. Briefly describe the current models of AGO-miRNA mediated translation inhibition.

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