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The O.J. Simpson trial highlighted the importance of proper evidence handling and sample processing. Despite overwhelming DNA evidence connecting Simpson to the double murder, the jury in his criminal trial acquitted him. Do you agree or disagree with their verdict? Why?

The sex of an individual can be determined using the amelogenin gene which returns different allele sizes present on the X (106 base pairs) and Y (112 base pairs) chromosomes.

A) You are typing a crime scene blood sample for sex and get only the 106 base pair band on your gel. What are your conclusions?

B) You are typing another sample and get only the 112 bp band on your gel? What can you determine about the sex of this individual?

C) What are some possible sources of error in genetic sex typing based on the amelogenin gene?

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