13. The component of the immune system which protects against pathogens without requiring prior sensitization is referred to as:
A. Humoral
B. Cellular
C. Innate
D. Adaptive
E. All categories require prior sensitization.
14. Specific immunity in a person includes
A. ingestion of bacteria by phagocytes.
B. involvement of helper T cells and B cells.
C. development of inflammation around a cut.
D. production of lysozymes in tears.
15. Situations leading to active immunity include a
A. baby receiving antibodies through the placenta prior to birth.
B. baby receiving antibodies in the mother's milk one month after birth.
C. baby receiving a vaccination against diptheria three months after birth.
D. all of the above
16. In humans, nonspecific immunity includes
A. production of antibodies by plasma cells.
B. different responses for different bacteria.
C. phagocytosis of bacteria by neutrophils.
D. presentation of material to a T cell by a phagocyte.
17. Non-specific immunity in mammals includes
A. the action of lysozymes in tears and saliva.
B. the production of antibodies after infection.
C. the production of memory cells.
D. the action of T helper cells.
18. Antibodies crossing the placenta from mother to fetus is an example of:
A. vaccination
B. cell-mediated immunity
C. passive immunity
D. active immunity
19. Which of the following is not true for Antigen Presenting Cells (APS)?
A. called Langerhans cells in epidermis
B. have same external marker proteins as macrophages
C. have a high concentration of HLA Class II antigens
D. all are highly ameboid and phagocytic
20. "A", and "B", and "C" HLA proteins are:
A. found on all cells of the body
B. found only on immunocompetent cells
C. essential to complement activation
D. phagocytized by activated macrophages
21. "A", & "B", & "C", and "DR", & "DP", & "DQ" HLA proteins are:
A. found on all cells of the body
B. found only on immunocompetent cells
C. essential to complement activation
D. phagocytized by activated macrophages
22. Which of the following is true concerning Natural Killer (NK) cells?
A. important in the production of antibodies.
B. non-specifically kill virally infected and tumor cells.
C. only kill cells after being activated by interaction with APCs.
D. they are known as Langerhans cells when found in the thymus
23. Complement proteins are capable of:
A. activating B cells to produce antibody
B. directing Natural Killer cell activity
C. lysing foreign cells that have antibody bound to them
D. being presented by APCs
24. Which of the following is not true for B-lymphocytes?
A. circulate in the bloodstream
B. found in the lymphatic nodes
C. develop and mature in the Thymus gland
D. capable of differentiating into plasma cells.
25. Tumor-cell lysing ability is not seen with which of the following:
A. delayed hypersensitivity (Tdth) cells
B. macrophages
C. activated Killer cells
D. cytotoxic T-cells
26. Which of the following is least phagocytic?
A. neutrophil
B. dendritic cell
C. macrophage
D. plasma cell
27. Which of the following does not function as an Antigen Presenting Cell (APC).
A. dendritic cell
B. reticulocyte
C. macrophage
D. langerhans cell
28. Which of the following is carried out by specialized cells circulating in blood and lymph.
A. humoral immunity
B. cell mediated immunity
C. innate immunity
D. the trash
29. Which of the following are special immune-system proteins circulating in blood and lymph.
A.complement
B.MHC Class I proteins
C.antigens
D.epitopes
30. Which of the following is not an activity of Ig
A. opsonization
B. complement activation
C. viral neutralization
D. antigen processing
31. B cell surface-bound antibody is most likely to be:
A. IgA
B. IgE
C. IgG
D. IgM
32. Which of the following is true for T-lymphocytes?
A. highly phagocytic, microbe-killing cells
B. first found in the T-nodes of T-birds
C. originate from stem cells in the Thymus gland
D. capable of stimulating or suppressing immune function.
33. The normal ratio of CD4:CD8 cells is 2:1. Why does this ratio become inverted in a patient with AIDS.
A. clonal expansion of Th cells
B. clonal expansion of Ts cell
C. loss of Th cells
D. increase in CD8 cells
Matching
A = true for Class 1 HLA proteins
B = true for Class 2 HLA proteins
C = true for both Class 1 and Class 2 HLA proteins
D = true for neither
34. found on all nucleated cells of the body A
35. expressed on T cells following activation
36. involved in communication between immunocompetent cells
37. closely associated with viral protein on surface of virally-infected host cell.
38 closely associated with antigen epitope on surface of antigen presenting cell.
39. one "set" -comprised of six different protein molecules- three inherited from each parent.
40. include complement system proteins.
Matching
1. Cells which are actively manufacturing antibodies
2. Cells which are capable of making antibodies once activated
3. Migratory cells capable of presenting antigen
4. Cells capable of killing virally infected cells (MHC-restricted)
5. Cells capable of killing tumor cells (no MHC-restriction)
6. Cells which are capable of stopping the immune response
7. WBCs most efficient at phagocytosis and killing of bacteria
8. Precursors of platelets
9. Immature red blood cells
10. Special proteins capable of binding to a specific antigen
11. Cells which secrete lymphokines to activate other immunocompetent cells
12. IL1 and TNFa, for example
A. Neutrophils
B. Immunoglobulin
C. Plasma cells
D. Reticulocytes
E. Lymphokines
AB. Macrophages
AC. Megakaryocytes
AD. Natural killer cells
AE. Cytotoxic T cells
BC. Suppressor T cells
BD. Helper T cells
BE. B cells