The carbonic anhydrase in proximal tubule epithelial cells, Ask an Expert

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The carbonic anhydrase in proximal tubule epithelial cells are particularly sensitive to inhibition by the medication, "Topamax." What is the step-by-step explanation of how the inhibitory action of how Topamax caused the disturbances in a person's blood chemistry, who was told she had metabolic acidosis as result of taking this medication.

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