Suppose you found an overly high level of pyruvate in a patient's blood and urine. a) One possible cause is a genetic defect in the enzyme pyruvate dehydrogenase. Describe the enzymes, cofactors, intermediates, and products of the pyruvate dehydrogenase complex. b) Another plausible cause for the high level of pyruvate in the patient's blood and urine is a specific vitamin deficiency. Which human disease is known for the deficiency of that vitamin in diet? Explain why the deficiency of that vitamin would account for high levels of pyruvate to be excreted in the urine. c) How would you determine which explanation, faulty/deficient enzyme or vitamin deficiency, is correct?