Question: Suppose that a series of compounds has been discovered in Neurospora. Compounds A-F appear to be members of an enzyme pathway. Several mutations have been identified and strains 1-4 each contain a single mutation. Shown below are five possible pathways. Choose the pathway that best fits the data presented. [Growth in minimal media with supplements is shown by (+), no growth is shown by (o)]
media supplement
|
Strain
|
A
|
B
|
C
|
D
|
E
|
F
|
|
1
|
o
|
o
|
o
|
+
|
o
|
o
|
|
2
|
o
|
o
|
o
|
o
|
o
|
+
|
|
3
|
o
|
o
|
o
|
o
|
+
|
+
|
|
4
|
o
|
o
|
+
|
o
|
o
|
o
|
a. A ? B ? C ? D ? E ? F
b. A ? B ? C ? F ? E ? D
c. A ? B ? C ? D
|
E ? F
d. A ? B ? C ? D
|
E ? F
e. A ? B ? C ? D
|
E ? F