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How frequently in the DNA (i.e., every how many base pairs) would you find the following restriction enzyme sequences in the DNA of an organism? Assume random and equal distribution of nucleotides and a 50:50 ratio of AT:GC.

1) Hpa II 5' -CCGG- 3'
2) Nae I 5' - GCCGGC- 3'
3) Fse I 5' -GGCCGGCC- 3'

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