Ask Question, Ask an Expert

+1-415-315-9853

info@mywordsolution.com

Ask Biology Expert

Patients in shock experience reduced delivery of oxygen to tissues, reduced activity of the pyruvate dehydrogenase complex, and raised anaerobic metabolism. Excess pyruvate is transformed to lactate, that accumulates in tissues and in the blood, causing the lactic acidosis.

a) Since oxygen is not a reactant or a product in the citric acid cycle, describe why do low levels of oxygen reduce the activity of the pyruvate dehydrogenase complex?

b) To alleviate the lactic acidosis, shock patients are sometimes given dichloroacetate that inhibits pyruvate dehydrogenase kinase. describe how does this treatment influence the activity of the pyruvate dehydrogenase complex?

Biology, Academics

  • Category:- Biology
  • Reference No.:- M937153

Have any Question? 


Related Questions in Biology

Explain why nbspin psoriasis is an nbspthe cells in the

Explain why  in Psoriasis is an  the cells in the dermis and epidermis thickened. Decreased cell maturation occurs in psoriasis  as a result of? Reference/s  must be provided to make  sure the  information  you are tutor ...

Biodiesel fuel is produced from oils synthesized by and

Biodiesel fuel is produced from oils synthesized by and harvested from living plants. How does the use of biodiesel fuel compare to the use of fossil fuels with respect to the amount of carbon dioxide released into the a ...

Clearly explain why health outcome is so much more than a

Clearly explain why health outcome is so much more than a combination of health care, individual behaviors, and/or genetics?

How does presence of both high and low affinity operators

How does presence of both high and low affinity operators allow for coordination of DNA repair, recombination bypass, and translesion synthesis in response to varying levels of DNA damage?

What water depth do reef corals prefer how does water depth

What water depth do reef corals prefer? How does water depth control coral growth? Explain the development of atolls.

Assignmentlife offers us choices and what an older part of

Assignment Life offers us choices, and what an older part of the forebrain, the limbic system, chooses is to feel better right away. The conscious forebrain, the cerebral cortex, knows that this can be short-sighted and ...

Describe the major events involved in image formation on

Describe the major events involved in image formation on the retina, and list in the correct order the components of the eye that light passes through on its way to the retina. Describe the specific consequences of any a ...

What is the process of dna replication please include

What is the process of DNA replication? Please include descriptions and possibly diagrams to further explain the process.

The a and b loci are 10 cm apart a plant with a genotype

The A and B loci are 10 cM apart. A plant with a genotype aaBB is crossed to plant with a genotype of AAbb. If an F1 plant is self pollinated, what proportion of the progeny will be homozygous dominant or homozygous rece ...

Trace the path of a sperm out of the male body and the path

Trace the path of a sperm out of the male body and the path of a sperm into the female body to an oocyte.

  • 4,153,160 Questions Asked
  • 13,132 Experts
  • 2,558,936 Questions Answered

Ask Experts for help!!

Looking for Assignment Help?

Start excelling in your Courses, Get help with Assignment

Write us your full requirement for evaluation and you will receive response within 20 minutes turnaround time.

Ask Now Help with Problems, Get a Best Answer

Section onea in an atwood machine suppose two objects of

SECTION ONE (a) In an Atwood Machine, suppose two objects of unequal mass are hung vertically over a frictionless

Part 1you work in hr for a company that operates a factory

Part 1: You work in HR for a company that operates a factory manufacturing fiberglass. There are several hundred empl

Details on advanced accounting paperthis paper is intended

DETAILS ON ADVANCED ACCOUNTING PAPER This paper is intended for students to apply the theoretical knowledge around ac

Create a provider database and related reports and queries

Create a provider database and related reports and queries to capture contact information for potential PC component pro

Describe what you learned about the impact of economic

Describe what you learned about the impact of economic, social, and demographic trends affecting the US labor environmen