Ask Question, Ask an Expert

+1-415-315-9853

info@mywordsolution.com

Ask Biology Expert

Patients in shock experience reduced delivery of oxygen to tissues, reduced activity of the pyruvate dehydrogenase complex, and raised anaerobic metabolism. Excess pyruvate is transformed to lactate, that accumulates in tissues and in the blood, causing the lactic acidosis.

a) Since oxygen is not a reactant or a product in the citric acid cycle, describe why do low levels of oxygen reduce the activity of the pyruvate dehydrogenase complex?

b) To alleviate the lactic acidosis, shock patients are sometimes given dichloroacetate that inhibits pyruvate dehydrogenase kinase. describe how does this treatment influence the activity of the pyruvate dehydrogenase complex?

Biology, Academics

  • Category:- Biology
  • Reference No.:- M937153

Have any Question? 


Related Questions in Biology

Ocean systemsaccording to the law of conservation of energy

Ocean Systems According to the law of conservation of energy, energy cannot be created or destroyed, but it can change from one form to another 1. A boy doing a cannonball into the pool. He went from potential to kinetic ...

For this assignment you will think about your individual

For this Assignment you will think about your individual health and health risks. What genetic diseases or problems might you face during your lifetime? Predisposition to heart disease, breast cancer, diabetes? You may c ...

A man and a woman both have polydactyly ie six fingers on

A man and a woman both have polydactyly (i.e., six fingers on each hand), a trait which is determined in this example by a single gene. They have four children, none of whom have polydactyly. What is the probability thei ...

Explain how the decline in genetic diversity with distance

Explain how the decline in genetic diversity with distance from Africa supports the Out of Africa hypotheses.

Describe the major events involved in image formation on

Describe the major events involved in image formation on the retina, and list in the correct order the components of the eye that light passes through on its way to the retina. Describe the specific consequences of any a ...

Determining whether clean groundwater has become dirty and

Determining whether clean groundwater has become dirty and what caused any contamination is a complex pursuit. Stephen Osborn and three colleagues from Duke University set out to learn whether drinking water was really b ...

What are the primary differences between the sympathetic

What are the primary differences between the sympathetic and parasympathetic nervous systems?

What is the relationship between the fields of taxonomy

What is the relationship between the fields of taxonomy, systematics and cladistics?

When we activate multiple motor units their individual

When we activate multiple motor units their individual force combine to produce a greater force through what?

Antropoligy online descution one paragraph and two

Antropoligy online descution One paragraph and two reply Patterns of Adaptation" How do humans adapt to environmental challenges? In this lesson, experts explore this question from many angles. The difference between acc ...

  • 4,153,160 Questions Asked
  • 13,132 Experts
  • 2,558,936 Questions Answered

Ask Experts for help!!

Looking for Assignment Help?

Start excelling in your Courses, Get help with Assignment

Write us your full requirement for evaluation and you will receive response within 20 minutes turnaround time.

Ask Now Help with Problems, Get a Best Answer

WalMart Identification of theory and critical discussion

Drawing on the prescribed text and/or relevant academic literature, produce a paper which discusses the nature of group

Section onea in an atwood machine suppose two objects of

SECTION ONE (a) In an Atwood Machine, suppose two objects of unequal mass are hung vertically over a frictionless

Part 1you work in hr for a company that operates a factory

Part 1: You work in HR for a company that operates a factory manufacturing fiberglass. There are several hundred empl

Details on advanced accounting paperthis paper is intended

DETAILS ON ADVANCED ACCOUNTING PAPER This paper is intended for students to apply the theoretical knowledge around ac

Create a provider database and related reports and queries

Create a provider database and related reports and queries to capture contact information for potential PC component pro