Ask Question, Ask an Expert

+1-415-315-9853

info@mywordsolution.com

Ask Biology Expert

A colleague has isolated several mutants that behave normally at low temperature, but at high temperatures exhibit anomalous behavior before or during S phase. You suggest that she characterize the mutant phenotypes at high temperatures in more detail by determining if the pre-replicative complex (pre-RC) forms normally and investigating if the replication origins can fire to initiate DNA synthesis. Once she has finished the suggested experiments, she returns for your help in interpreting the data. Match the phenotype in the left column with a proposed defect in protein function from the right column that may describe each phenotype.


A. Cells arrest in G1with normal pre-RC
B. Cells arrest in G1with no pre-RC
C. Origins fire more than once during a single S phase
D. Cells replicate DNA normally but cannot proceed to M phase


1. S cyclins cannot be degraded
2. Cdc6 cannot bind ORC
3. S cyclins cannot bind Cdks
4. Cdc6 cannot be ubiquitinated

Biology, Academics

  • Category:- Biology
  • Reference No.:- M943183

Have any Question? 


Related Questions in Biology

Case study 20 food for a low-income familysarah is a

Case Study 20: Food for a Low-Income Family Sarah is a 30-year-old mother of two young children, ages 3 and 5. Her husband was recently disabled in a car accident and has been unable to work for 6 months. Sarah works par ...

State without explanation any three common features

state without explanation, any three common features regarding reptiles, birds and mammals.

Gene technologygene technology carries with it social and

Gene Technology Gene technology carries with it social and ethical implications-many of which engender personal views and discussion. Select one (1) of the following biotechnology topics to write about:  Genetically modi ...

You read in the newspaper about a recently approved

You read in the newspaper about a recently approved prescription drug that has suddenly been withdrawn from the market because of severe adverse effects and several deaths. Discuss why this can still occur despite years ...

Question 1 an example of a community isone giant individual

Question 1 An example of a community is one giant individual kelp. a kelp forest plus all of the physical factors affecting it. all physical factors affecting a kelp forest. a kelp forest plus all organisms living in it. ...

Create a patient scenario but dont give away the

Create a patient scenario but don't give away the disease.  First explain the terms opportunistic and true pathogen. Also differentiate between syndrome, signs and symptoms of disease so everyone will have an idea of wha ...

1 a portion of a gene contains the following sequence

1. A portion of a gene contains the following sequence: GAAGGAGTAGCA. After transcription, it gives the mRNA sequence: CUUCCUCAUCGU, which is then translated to the amino acid sequence leucine-proline-histidine-arginine. ...

Select one of the topics research the topic thoroughly and

Select One of the Topics, Research the Topic Thoroughly and Write a Concise Research Paper Companion Animal Medicine Most of the concepts that apply to humans also apply to our companion animal friends, an important thin ...

Weve all had experiences where we have been frustrated by a

We've all had experiences where we have been frustrated by a decision that our supervisor made. You have probably blamed this decision on your boss being "closed-minded," "stubborn," or "pigheaded." But after reading the ...

Huntingtons disease affects individuals late into adulthood

Huntington's disease affects individuals late into adulthood. Given what you know about how Natural Selection works, explain why Huntington's disease hasn't been eradicated from the population.

  • 4,153,160 Questions Asked
  • 13,132 Experts
  • 2,558,936 Questions Answered

Ask Experts for help!!

Looking for Assignment Help?

Start excelling in your Courses, Get help with Assignment

Write us your full requirement for evaluation and you will receive response within 20 minutes turnaround time.

Ask Now Help with Problems, Get a Best Answer

WalMart Identification of theory and critical discussion

Drawing on the prescribed text and/or relevant academic literature, produce a paper which discusses the nature of group

Section onea in an atwood machine suppose two objects of

SECTION ONE (a) In an Atwood Machine, suppose two objects of unequal mass are hung vertically over a frictionless

Part 1you work in hr for a company that operates a factory

Part 1: You work in HR for a company that operates a factory manufacturing fiberglass. There are several hundred empl

Details on advanced accounting paperthis paper is intended

DETAILS ON ADVANCED ACCOUNTING PAPER This paper is intended for students to apply the theoretical knowledge around ac

Create a provider database and related reports and queries

Create a provider database and related reports and queries to capture contact information for potential PC component pro