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Salmonella enterica is closely related to Escherichia coli. It can be infected with the F plasmid, which can integrate into the chromosome to produce Hfr strains.These can be mated with F- E. coli to study the order and time of entry of genetic markers. The data shown here pertain to times of entry of four genetic markers in crosses of E. coli Hfr x E.coli F- and S. enterica Hfr x E.coli F- .

ile met pro arg
E. coli Hfr x E. coli F- 28 20 6 22
S. enterica Hfr x E. coli F- 4 22 47 18
(numbers refer to time in minutes)

(a) How do the genetic maps of E. coli and S. enterica compare with respect to these genes?
(b) What are the origin and direction of transfer in each Hfr?
(c) How fast does an S. enterica Hfr transfer chromosomal DNA relative to an E. coli Hfr?

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