(Answered) Rotenone is a poison that acts by blocking electron flow in

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Rotenone is a poison that acts by blocking electron flow in Complex 1. Predict the effect of rotenone on the following processes.

a. O2 utilization by the electron transport chain (up or down)

b. ATP production via oxidative phosphorylation (up or down)

c NADH levels in the matrix of the mitochondria (up or down)

After several hours of rotenone inhibition, will complex II continue to pass electrons from succinate to FAD (making FADH2) and finally ubiquinone? Why or why not?

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