Question 1

Thalassemia major (Cooley's Anemia)Upload a photograph (or scanned and saved image) of the pedigree you constructed tracing the thalassemia allele based on the family information provided. Your pedigree must include a list of the genotypes next to each individual in the pedigree and a key identifying which allele is represented by the capital and lower case letters.

Question 2

Part 1: Thalassemia major (Cooley's Anemia)

Based on the pedigree you constructed and the information provided, identify the inheritance pattern for this trait. Be sure to identify whether the trait is autosomal or sex-linked, and dominant or recessive.

autosomal dominant
autosomal recessive
sex-linked dominant
sex-linked recessive

Question 3

Part 1: Thalassemia major (Cooley's Anemia)

Based on the pedigree you constructed and information provided explain how you identified the inheritance pattern.

Question 4

Part 1: Thalassemia major (Cooley's Anemia)

Assume that Linda is heterozygous for thalassemia. John and Linda have a child. What is the likelihood (in percent) that this child will inherit two thalassemia alleles?

A. 100%
B. 75%
C. 50%
D. 25%

Question 5

Part 1: Thalassemia major (Cooley's Anemia)

Assume thatLinda is homozygous dominant (normal) for the thalassemia gene. John and Linda have a child. What is the likelihood (in percent) that this child will inherit thalassemia?

A. 100%
B. 75%
C. 50%
D. 0%

Question 6

Part 1: Thalassemia Major (Cooley's Anemia)

Explain how you determined the genotypes of John's parents.

Question 7

Part 2: Duchenne Muscular Dystrophy

Upload a photograph (or scanned and saved image) of the pedigree you constructed tracing the muscular dystrophy allele based on the family information provided. Your pedigree must include a list of the genotypes next to each individual in the pedigree and a key identifying which allele is represented by the capital and lower case letters.

Question 8

1. Part 2: Duchenne Muscular Dystrophy

Based on the pedigree you constructed and the information provided, identify the inheritance pattern for this trait. Be sure to identify whether the trait is autosomal or sex-linked, and dominant or recessive.

A. autosomal dominant
B. autosomal recessive
C. sex-linked dominant
D. sex-linked recessive

Question 9

Part 2: Duchenne Muscular Dystrophy

Based on the pedigree you constructed and the information provided explain how you identified the inheritance pattern.

Question 10

Part 2: Duchenne Muscular Dystrophy

What is the probability that Vanessa and George will produce a daughter with muscular dystrophy?

A. 100%
B. 50%
C. 25%
D. 0%

Question 11

Part 2: Duchenne Muscular Dystrophy

What is the probability that Vanessa carries the muscular dystrophy allele? How did you determine this?