Question 1. Which of the following is a protein produced by the immune system in response to an infectious agent?
macrophage
antigen
antibody
riboflavin

Question 2. Several inherited deficiencies in the Complement system occur in humans. Which of the following would be the most severe?
Deficiency of C3
Deficiency of C5
Deficiency of C6
Deficiency of C10
Deficiency of C7

Question 3. Macrophages and neutrophils are primary components in which branch of the immune system?
innate
adaptive

Question 4. The best definition of antigen is:
a red or white blood cell
A foreign substance that elicits an immune response
A protein that combines with antibodies
an allergic reaction

Question 5. B cells are part of which branch of the immune system?
innate
lymphatic
external
acquired

Question 6. What is the primary role of neutrophils in an immune response?
immune system deactivation
Complement activation
professional phagocyte
all of the above

Question 7. Which of the following can activate Natural killer (NK) cells?
the bacterial cell wall component LPS
interferon beta
interferon alpha
all of the above

Question 8. Macrophages are activated by antigens coated in which Complement protein?
C16
C1
C6
C3

Question 9. Which of the following cell types is NOT involved in innate immunity? (Points : 3)
T cell
macrophage
neutrophil
natural killer cells

Question 10. The Complement protein cascade is the same for the classical pathway, alternative pathway, and lectin pathway beginning with the activation of:
C1
C2
C3
C5

Question 11. Natural killer cells secrete chemicals that activate ___________.
the acquired immune system only
red blood cells
both the innate and acquired immune system
the innate immune system only

Question 12. An immune cell ingests dead cells, bacteria, and viral components and then internally digests these agents. This process is known as:
reciprocal elimination
inflammation
cellular elimination
phagocytosis

Question 13. A B cell cannot be activated without the help of a specialized T cell.
True
False

Question 14. Which of the following recognizes antigens displayed on host cells with MHC II?
Killer T cell
inactive B cell
TH cell
natural killer cell

Question 15. Which of the following is an antigen presenting cell (APC)?
dendritic cell
natural killer cell
killer T cell
helper T cell

Question 16. Which class of antibodies are the first to respond to an infection?
IgM
IgA
IgE
IgG

Question 17. Which class of antibodies indicate prior exposure to an antigen?
IgA
IgE
IgG
IgM

Question 18. MHC class __ molecules can be found on almost all cells in the human body:
I
II
III
IV

Question 19. A B cell is referred to as _______when it has not been exposed to an antigen.
raw
novel
naïve
unmarked

Question 20. immunity involving T cells is referred to as______ immunity.
cellular
innate
destructive
lytic

Question 21. Which of the following is NOT used by cytotoxic T cells to kill their target cells?
Perforin
MHC II molecule
Granzyme
Fas Ligand (FasL)

Question 22. The T cell that interacts with MHC I molecules is
T Helper Cell
regulatory T Cell
TH17 Cell
cytotoxic T Cell

Question 23. Which of the following is considered the major antigen presenting cell in the body?
neutrophil
B cell
dendritic Cell
T Helper Cell

Question 24. A T cell that expresses the CD8 receptor on its surface is
T Helper Cell
cytotoxic T Cell
plasma Cell
dendritic Cell

Question 25. Which of the following is NOT a subtype of Helper T cell?
Th1
Th6
Th17
Th2

Question 26. The helper T cell is activated by which other cell?
an activated NK cell
an activated drone cell
an activated dendritic cell
a neutrophil

Question 27. Which of the following does NOT interact with T helper cells?
B cells
dendritic Cells
cytotoxic T Cells
Red Blood Cell

Question 28. The most common location to find a naïve T cell is:
Lymph node
Site of acute infection
Site of chronic infection
saliva

Question 29. Where do most lymphocytes come in contact with their antigen?
Bone Marrow
Spleen
Lymph node
Liver

Question 30. When a lymph node becomes swollen, the most common reason is
Infection nearby
Blocked lymphatic vessel
Blocked capillary vessel
Heat exhaustion

Question 31. Which event is the primary reason that the innate and cellular immune systems may be turned down or off?
more B cells are activated
decrease in free antigen
antibody production is stopped
T cells are short-lived

Question 32. Which of the following is an example of a primary lymphoid organ?
mucosal-associated lymphoid tissue (MALT)
lymph node
bone marrow
spleen

Question 33. T regulatory cells (T regs) function to
Activate naïve Cytotoxic T cells
Activate dendritic cells
Downregulate an immune response
Regulate production of T and B cells in bone marrow

Question 34. Which organ is responsible for screening blood for the presence of pathogens?
lymph nodes
liver
bone marrow
spleen

Question 35. The human immune system ignores 'commensal' bacteria because:
the bacteria are too small to be detected
the bacteria do not attach to tissue
the immune system does not respond to any bacteria
the immune system has adapted to see them as harmless.