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Question 1

Which of the following can be used as a transneuronal tracer (a tracer that labels multiple neurons in series)?

Pseudorabies virus

Kainic acid

Golgi staining

Fos protein
5 points
Question 2



Researchers using CT or MRI ____________________.

do not have to obtain permission from either the patient or the family.

can study the living brain without operating on the patient.

must first anesthetize the patient.

must first shave the patient's head.
5 points
Question 3



________ is used to produce an excitotoxic lesion in brain.

Radiofrequency current

Hydrochloric acid

6-hydroxydopamine

Kainic acid
5 points
Question 4



________ labeling involves injecting something that is taken up by the cell bodies and transported down the axon toward the terminal.

Histograde

Anterograde

Retrograde

Nuclear
5 points
Question 5



Which of the following is NOT an implication of the ablation technique?

The interpretation of the results from a lesion study is straightforward.

Ablation studies indicate which brain region is responsible for a specific behavior.

Investigators infer the function of a brain area by the changes in behavior that occur after ablation of the region.

Lesions can be produced by removing brain tissue.
5 points
Question 6



_______ is a nuclear protein produced when neurons are activated.

fos

glycine

Kainic acid

GABA
5 points
Question 7



Immunocytochemical methods are used to ____________________.

selectively destroy axons.

inhibit fast axoplasmic transport.

locate peptides and proteins.

provide a view of a "slice" of the human brain.
5 points
Question 8



The concept of concordance ____________________.

Is shown when two twins exhibit the same trait.

Is shown when a trait is different between two twins

Is apparent when the results of 2 studies are similar.

Implies that genetics are not important for understanding human behavior.
5 points
Question 9



Which of the following techniques is commonly used to examine the metabolic activity of human brain?

Fos labeling.

Labeling with PHA-L.

Autoradiography.

Position emission tomography.
5 points
Question 10



Which of the following would be used to implant an electrode into rat brain?

Radiofrequency device

Microdialysis probe assembly

Electroelecording instrument

Stereotaxic instrument.
5 points
Question 11



The metabolic activity in the brain of a laboratory animal can be measured by giving an injection of _____ and analyzing the results using _____.

saline; electroencephalography

Fos; a PET scanner

fluorogold; in situ hybridization

2-DG; autoradiography
5 points
Question 12



A fixative performs all these functions except ____________________.

hardening tissue.

halting autolysis.

attaching tissue to a microscope slide.

killing destructive microorganisms.
5 points
Question 13



A substance that produces a color reaction within cytoplasmic proteins of a neuron would be expected to stain:

Synapses.

Vesicles.

Cell bodies.

Axon terminals.
5 points
Question 14



Which of the following would be used to stain cell bodies in a brain tissue section?

PHA-L.

Cresyl violet.

Formaldehyde.

Fluorogold.

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