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Question - A family of four that is made up from a 2 and 8-year-old. plus their parents were traveling from Europe to the USA. On the way, it was noticed that the 8-year-old boy is having fever, headache and his head was tilting to the right in addition there was some form of rash on his hands and feet. Their father was feeling very fatigued with flu like symptoms and a rash beginning to develop at the hands and some areas of his feet. The other two members of the family were doing very well. Upon arrival to the USA both the child and the father were admitted to the hospital. A spinal tap reflected the presences of Neisseria meningitidis in their CSF. The rash has spread more in the 8-year-old but it is no longer showing on his father. They have all been vaccinated against this bacterium.

I. Explain the pathogenesis of the disease in both the 8-year-old and the father and why their symptoms differ.

II. Explain why the mother and the 2-year-old did not have any symptoms of the disease.

III. Explain your method of treatment for both ill members and what precautions if any would take to protect the mother and the 2-year-old.

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