Q1) What is a T cell? Where is it formed? Where is it ‘educated' to recognize self? And, what are some of the roles in cell-mediated immunity?

Q2)_____ One of the main roles of a B cell (B lymphocyte) is to

a) recognize self from nonself and aid in cell mediated
b) recognize immunoglobulins in humoral immunity
c) produce antigens to be recognized by antigen presenting cells
d) mature into antibody-producing plasma cells in the bone marrow

Q3)____Type I diabetes, lupus, and multiple sclerosis are all examples of:

a) sugar related insulin dependent disease
b) genetic disease with a distinct inheritance pattern
c) autoimmunity most often showing up after childhood
d) organ specific dysfunction disease

Q4) There are 5 types of immunoglobulins. List them

i-
ii-
iii-
iv-
v-

Identify which one is the most protective after vaccination? ______________________

Identify which one is passed from maternal breast milk to infant? _________________

Q5)_____ Celiac disease is an autoimmune disease which can lead to the destruction of villi in the intestine. What is not a possible consequence?

a) inability to absorb nutrients
b) weight gain due to more absorbed wheat protein
c) osteoporosis
d) hair loss
e) iron deficiency and anemia

Q6) Choose an autoimmune disease (either from our discussions or a separate one) and expand on it here.Find a primary research article reference to provide. (Primary research is the actual research- you will need to have one ready for the final exam, so here is another chance to find one). Highlight ...What causes? What symptoms?

Q7) Prostaglandins are hormones which have two effects-and NSAIDs can help block these two effects, but they can also be‘hard on the tummy' (hurt the gastric organ).

List the two effects:

Define NSAIDs:

Explain why they can cause stomach problems:

Q8)  _____Environmental and work exposures can lead to toxic effects that affect the nervous system, so how could eating a fish be bad for a pregnant woman?

a) fish have fatty acids that are healthy for all of us except pregnant women
b) fish can bioaccumulate methylmercury from coal plant and gold processing
c) fish can bioaccumulate gold from gold processing that harms the fetus
d)fish are not bad at all for pregnant women

Q9) _____ The first step in evaluating a patient is

a) to listen to the patient and take a medical history
b) to take vital symptoms and listen to the signs from the patient
c) to run a less invasive MRI
d) form a hypothesis about what is wrong

Q10)  Which of the following would tell something to aid in diagnosis of a problem with the lungs?

a) auscultation
b) percussion
c) breathing rate 12-20 breathes per minute
d) all of the above

Q11) _____ Which of the following was not a test for the patient scenario Mr. Smith?

a) CBC Complete Blood Count
b) Chemistry Metabolic Panel CMP
c) Urine tests for overly high aldosterone secretion
d) K+ test for muscle, nerve, and cardiac function
e) Ultrasound of the adrenal

Q12) _____ If HCO3 is high then _________; if H+ is high then _________

a) alkalosis; alkalosis
b) alkalosis; acidosis
c) acidosis; alkalosis
d) acidosis; acidosis

Q13) The hormone that stimulates red blood cell production is called __________________ and is sometimes used in blood doping.

Q14) If blood plasma volume is _________due to doping, then blood pressure will be _________.

a) Low; low
b) Low; high
c) High; low
d) High; high

Q15)  Formed blood elements (main groups/ types of blood cells ) are _______________, ______________, and ____________________.

Q16) Oxygen-carrying protein in red blood cells' is called ________________________.

Q17) The site of production of red blood cells and most white blood cells is ____________________

Q18) Large numbers of abnormal white blood cells are typical for a neoplastic disorder is called _____________.

Q19) I hope you are doing your module practice quizzes so some of these questions are easy for you, but you don't need the module to answer this one correctly. In fact, our module has an error in the blood type table-a potentially fatal error if you learn it incorrectly. Can you find it? People with O type blood are called universal _________________ because they have _____________antigens, but they still have antibodies against _______ and _______.

How would you explain type A?

Type B?

Type AB?

Q20) Contraction of the heart chambers is called _________________ and when ventricles contract in blood pressure measurements it is the which (top or bottom) number?______
Relaxation of the heart chambers is _____________.

Q21) A heart disease that develops after a streptococcal infection is called ____________________

Q22) A disorder that results from blocked blood flow to the heart is an accumulation of plaques on the inside of arterial walls are typical for an arterial disease called ____________________

Q23) ___________________ are caused by the blockage of blood supply to the brain by a blood clot embolus or other agent resulting in interruption of the oxygen transport to the brain and leading to neurological damage or death.

Q24) Emulsification of lipids is accomplished by ___________________ produced by the liver

a) heme
b) bile
c) gallbladder
d) cholesterol

Q25) A disorder characterized by inability to digest lactose from milk is _____________________

a) milk intolerance
b) milk allergy
d) lactose intolerance
e) fructose, sorbitol and lactose intolerance

Q26) When gastric problems arise, discomfort and serious complications can occur. Choose one to describe further.

-GERD - type of gastro-esophageal reflux
-HeIicobacterpylori
-loss of intrinsic factor release
-overuse of antacid.