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Q1. A man heterozygous for a disease gene D is also heterozygous for an RFLP linked at the distance of 4 map units from the disease gene. His chromosomal arrangement is D morph-1/d morph-2. What percentage of his sperm will be D morph-2?

Q2. The probability of having a child with a chromosomal abnormality increases as a woman's age increases over 40 years old. After reading section on oogenesis, why do you think this is the case? Understand the section on spermatogenesis. Do you think the age of the man is as important in determining the chance of chromosomal abnormalities? Why or why not give reasons.

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