Problem:

You decide to use different bacterial strains (each having one protein of the replication machinery mutated) in order to examine the role of individual proteins in the normal process of DNA replication.

Question: What part of the DNA replication process would be most directly affected if a strain of bacteria lacking DNA primase were used to make a cell extracts?

a. Initiation

b. Okazaki fragment synthesis

c. leading - strand elongation

d. lagging - strand completion

Any help would be greatly appreciated!