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Problem:

Therapeutic antibodies, for example Rituximab which recognises CD20 on B lymphoma cells, can cause adverse effects.

One reason behind these adverse effects could of course be an over-response of immune cells stimulated by the Fc region of antibodies attached to lymphona cells.

However, it could also be thinkable that the immune system launches a response against the antibody itself, recognising it as foreign.

Question: Does this occur? Give its detailed discription.

Question: What part of the injected antibody acts as the epitope recognised by immune cells as foreign?

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Category:- Biology
Reference No.:- M91149889

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