Problem:

Question: A couple consults a physician because they have been unable to conceive. A semen sample collected from the man shows no sperm. On physical examination, the man has Gynecomastia and testicular atrophy. Testicular biopsy shows sparse, completely hyalinized seminiferous tubules with a complete absence of germ cells and only rare sertoli cells. Leydig cells are present in large clumps between the hyalinized tubules. Which of the following is the most likely diagnosis?

a) Alcoholism
b) Fragile X syndrome
c) Klinefelter syndrome
d) Testicular feminization syndrome
e) Turner syndrome

Please select correct answer and also provide explaination.