Problem:

Question 1:  Define: Central dogma of molecular biology, haplosufficient and haploinsufficent loss of function, gain of function, transcription unit, transcription, transcriptome, genome, proteome, forward genetics, reverse genetics.

Mutations and Repair system genetics question:

Question 2: Should be able to define the following:
Transition, tranversion, synonymous, conservative missense, non-conservative missense, non-sense mutations, indel mutations and frame shift mutations, loss of function mutations, gain of function mutations, null mutation (genetic null), knockout mutations, knockdown mutations.

Explain thoroughly.