Problem:

Question 1: What methods have been used traditionally to diagnose cancers?What issues arise from these methods?

Question 2: Look up the definition of the word pleiotropy. How does this concept help explain why scientists are beginning to classify tumors based on their molecular characteristics instead of their tissue characteristics?

Question 3: Explain a microarray study.What does it mean if a spot is red? Or Green? Or yellow?

Question 4: Based on this data, which genes' expression could be used as diagnostic tools for patients?

Question 5: How does DNA Methylation impact gene expression?How might a change in DNA Methylation status lead to tumor growth?

Please read all the questions carefully and answer them.