Problem:

Question 1: Suppose a person developed a mutation in a somatic cell which diminishes the performance of the bodys natural cell cycle control proteins. This mutation resulted in cancer yet, but was effectively treated with a cocktail of cancer-fighting techniques. Is it possible for this persons future children to inherit this cancer causing mutation? Be specific when you explain why or why not.

Question 2: Why do cells which lack cell cycle control exhibit karyotypes which look physically different than cells with normal cell cycle.

Question 3: What are HeLa cells?

Question 4: Research the function of the protein called p53. What does this function do? Explain how it can affect cell cycle control.

Question 5: What is the Philadelphia chromosome? How is this chromosome related to cancer? Identify how this chromosome appears physically different on a karyotype than it appears on a karyotype of normal chromosomes.

Include source of information for best answer.