Problem:

Question 1: List the experimental requirements of Koch's postulates, and explain the exceptions to the requirements.

Question 2: Given the limitations of Koch's postulates, what role do you see for molecular genetics and associated techniques in addressing the exceptions to the postulates?

Question 3: Cancer patients undergoing chemotherapy are normally more susceptible to infections. However, a patient receiving an antitumor drug that inhibited cell division was resistant to Salmonella. Provide a possible mechanism for the resistance.

Question 4: Describe the mode of action of each of the following antibiotics and explain what effect each one may have on host cells. Give an example of an organism that would be effectively treated for each drug.

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