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Problem:

Imagine that you have two neighboring populations (1 and 2) of a species. There is random mating within each population, so they are each in Hardy-Weinberg equilibrium for a locus with two alleles (A and a). In population 1, the frequency of the "A" allele is p = 0.8. In population 2, the frequency of the "A" allele is p = 0.2. Imagine that you generate a mixed population consisting of half individuals from population 1 and half individuals from population 2. [For parts (a), (b), and (d) below, you should show calculations that justify your answer, but you do not need to provide a written explanation.]

Required:

Question 1: Assuming no mating or reproduction has yet occurred in the mixed population, what are the allele and genotype frequencies in the mixed population?

Question 2: Is the mixed population in Hardy-Weinberg equilibrium? If not, is there an overrepresentation or underrepresentation of heterozygotes in the population relative to Hardy-Weinberg expectations?

Question 3: For question 2, you should have found that the population is not in Hardy-Weinberg equilibrium. This is an illustration of what is known as the Wahlund Effect, in which an overall (mixed) population can deviate from Hardy-Weinberg equilibrium if there are isolated subpopulations with different allele frequencies (even if each individual subpopulation is in Hardy-Weinberg equilibrium itself).

Briefly explain why the presence of isolated subpopulations within a population can have similar effects on genotype frequencies as inbreeding among close relatives within a population.

Question 4: Now imagine that the mixed population that you generated starts undergoing random mating. How many generations should it take for genotype frequencies to return to Hardy-Weinberg expectations?

Please provide discription of all the answers.

 

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  • Category:- Biology
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