Problemi have noticed that some tf binding sites are, Ask an Expert

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Problem:

I have noticed that some TF binding sites are located in the introns of the genes.

I am puzzled about whether the TF only binds to DNA in the initiation stage of transcription and will detach during transcription. (I am thinking if the TF bind to the sense strand, it will block the PoLII for transcription, thus they should be removed.)

Please provide some more detail about it.

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Category:- Biology
Reference No.:- M91162095

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