Problemi have noticed in a particular genome sequence of a, Ask an Expert

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Problem:

I have noticed in a particular genome sequence of a prokaryote that various regions in a sequence share similarity which is high(>80%) with known proteins. However, the start is not a methionine.

Required:

Question 1: Is this a dysfunctional 'protein' sequence?

Question 2: Are there alternative codons which translate those regions without a Met or fMet for that matter?

Technically, do all annotations of proteins have to start with a methionine?

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Biology, Academics

Category:- Biology
Reference No.:- M91149347

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