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Problem:

Fructose-1,6-bisphosphate aldolase catalyzes a reversable aldol condensation reaction during glycolysis to make D-glyceraldehyde-3-phosphate and dihydroxyacetone phosphate from fructose-1,6-bisphosphate. The enzyme has been shown to possess a nucleophilic lysine that forms a Schiff base intermediate during catalysis.

Draw a detailed electron-pushing mechanism for this reaction catalyzed by fructose-1,6-bisphosphate aldolase.

Feel free to invoke generic acids and bases (A-H an B:, respectively) as necessary.

Include source of information for best answer.

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  • Category:- Biology
  • Reference No.:- M91167905

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