Problem:

Based on their family histories, a couple knows that they are each heterozygous for alkaptonuria (remember that condition where black urine is produced).The alkaptonuria phenotype is autosomal recessive to the normal phenotype.The couple plan to have seven children.

Question: In a single birth, what is the probability of the couple having an affected child?

Question: In a single birth, what is the probability of the couple having an unaffected child?

Question: What is the probability that three children will be alkaptonuric and the other four normal?

Question: What is the probability that at least one of the children will be alkaptonuric?