Problem:

1)An individual with selective brain damage begins to show uncoordinated movements.

Required:

Question 1: Which region of the brain is likely to be affected? Please provide correct answer.

Question 2: How would you investigate neuronal activity in this brain region? Please explain.

2) Describe briefly the various ways in which neurons use both plasma membrane proteins and proteins on the endoplasmic reticulum to increase intracellular Ca2+ concentrations.