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1) describe why is the synthesis of mRNA a central issue for all the viruses?

2) Polio and HIV are both +ssRNA viruses which have much different strategies for replicating their genomes. After the viral genomes enter the cell (that is, post entry), describe the first step comprised in replication of each genome. Your explanation can comprise a diagram and should cover 1) the name of the synthesis reaction that takes place, 2) any molecules which act on the viral genome 3) whether these molecules are viral or host in origin, 4) the product(s) of this first step, and 5) which cellular compartment step 1 occurs in.

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