Ask Question, Ask an Expert

+1-415-315-9853

info@mywordsolution.com

Ask Biology Expert

1. The disease beriberi, which results from a dietary deficiency of vitamin B1 (Thiamine) is characterized by neurological and cardiac symptoms, as well as increased levels of pyruvate and alpha- ketoglutarate in the blood. How does a deficiency of thiamine account for the increased levels of pyruvate and alpha- ketoglutarate?

2. Patients in shock experience decreased delivery of oxygen to tissues, decreased activity of the pyruvate dehydrogenase complex, and increased anaerobic metabolism. Excess pyruvate is converted to lactate, which accumulates in tissues and in the blood, causing lactic acidosis.

a. Since oxygen is not a reactant or a product in the citric acid cycle, why do low levels of oxygen decrease the activity of the pyruvate dehydrogenase complex?

b. To alleviate lactic acidosis, shock patients are sometimes given dichloroacetate, which inhibits pyruvate dehydrogenase kinase. How does this treatment affect the activity of the pyruvate dehydrogenase complex?

3. The reaction for which the enzyme pyruvate kinase is named never occurs in the cell. Briefly discuss this.

Biology, Academics

  • Category:- Biology
  • Reference No.:- M924909

Have any Question? 


Related Questions in Biology

The rh disease of newborn maternal anibodies enter fetal

The Rh disease of newborn, maternal anibodies enter fetal circulation and destroy the red blood cells of tbe fetus. A mother with type o blood has both anti A and anti B antibodies, but may have a dozen type A children w ...

Schedule slippage and delays are common for project

Schedule slippage and delays are common for project managers to manage. Experience contributes to a project manager's ability to address schedule impacts. Discuss how organizations can utilize the Learning Theory and Pro ...

What is the state of the issue of genome engineering

What is the state of the issue of Genome engineering technology in Sweden? Are there laws governing the it? Is there a high level of controversy in Sweden over the ethical issues of Genome engineering technology? Why/why ...

What are the primary differences between a steroidlipid

What are the primary differences between a steroid/lipid soluble hormone and a protein hormone?

1 what is the scientific basis behind evolution please

1. What is the scientific basis behind evolution? Please explain your answer

1 give one hypothesis about the relationship between

1) Give one hypothesis about the relationship between protein sequence and protein color that you tested in the Aipotu I: Genetics & Biochemistry lab. 2) Give the genotype of each of the four starting strains of Aipotian ...

Discuss five different techniques used in the preparation

Discuss five different techniques used in the preparation of fermented products. please cite where you got the information please.

What are the ingredients in gatorade how does it provide

What are the ingredients in Gatorade how does it provide energy? In your opinion, should a person use this drink or supplement on a regular basis? Why or why not?

1 which type of vessels arteries or veins has more muscle

1) Which type of vessels, arteries, or veins, has more muscle fibers? What is the functional significance of this? 2) In general, we have no conscious control over smooth muscle or cardiac muscle function, whereas we can ...

Jerry coyne proposes a question at what point are the

Jerry Coyne proposes a question. At what point are the differences between populations large enough to make us call them different species? please answer question and defend answer.

  • 4,153,160 Questions Asked
  • 13,132 Experts
  • 2,558,936 Questions Answered

Ask Experts for help!!

Looking for Assignment Help?

Start excelling in your Courses, Get help with Assignment

Write us your full requirement for evaluation and you will receive response within 20 minutes turnaround time.

Ask Now Help with Problems, Get a Best Answer

Section onea in an atwood machine suppose two objects of

SECTION ONE (a) In an Atwood Machine, suppose two objects of unequal mass are hung vertically over a frictionless

Part 1you work in hr for a company that operates a factory

Part 1: You work in HR for a company that operates a factory manufacturing fiberglass. There are several hundred empl

Details on advanced accounting paperthis paper is intended

DETAILS ON ADVANCED ACCOUNTING PAPER This paper is intended for students to apply the theoretical knowledge around ac

Create a provider database and related reports and queries

Create a provider database and related reports and queries to capture contact information for potential PC component pro

Describe what you learned about the impact of economic

Describe what you learned about the impact of economic, social, and demographic trends affecting the US labor environmen