Ask Question, Ask an Expert

+1-415-315-9853

info@mywordsolution.com

Ask Biology Expert

1. The disease beriberi, which results from a dietary deficiency of vitamin B1 (Thiamine) is characterized by neurological and cardiac symptoms, as well as increased levels of pyruvate and alpha- ketoglutarate in the blood. How does a deficiency of thiamine account for the increased levels of pyruvate and alpha- ketoglutarate?

2. Patients in shock experience decreased delivery of oxygen to tissues, decreased activity of the pyruvate dehydrogenase complex, and increased anaerobic metabolism. Excess pyruvate is converted to lactate, which accumulates in tissues and in the blood, causing lactic acidosis.

a. Since oxygen is not a reactant or a product in the citric acid cycle, why do low levels of oxygen decrease the activity of the pyruvate dehydrogenase complex?

b. To alleviate lactic acidosis, shock patients are sometimes given dichloroacetate, which inhibits pyruvate dehydrogenase kinase. How does this treatment affect the activity of the pyruvate dehydrogenase complex?

3. The reaction for which the enzyme pyruvate kinase is named never occurs in the cell. Briefly discuss this.

Biology, Academics

  • Category:- Biology
  • Reference No.:- M924909

Have any Question? 


Related Questions in Biology

Case study over 30 children younger than 3 years of age

Case study: Over 30 children younger than 3 years of age developed gastroenteritis after visiting a local water park. These cases represented 44% of the park visitors in this age group on the day in question. Older indiv ...

Concerning a patient with autonomic dysreflexiawith what

Concerning a patient with autonomic dysreflexia: With what you know of the etiology for the hypertension, was labetalol a good choice for managing the blood pressure? Why or why not? If not, what other kind of drug do yo ...

Imagine you do a test cross between a purple-flowered pea

Imagine you do a test cross between a purple-flowered pea plant having serrated leaves (a dominant trait) and a white-flowered pea plant having smooth edges. If the purple-flowered plant is heterozygous for both traits, ...

Why was there such a diversity of species in such a small

Why was there such a diversity of species in such a small area? Could these species have been modified from an ancestral form that arrived on the Gal√°pagos Islands shortly after the islands were formed?

Imagine you do a test cross between a purple-flowered pea

Imagine you do a test cross between a purple-flowered pea plant having serrated leaves (a dominant trait) and a white-flowered pea plant having smooth edges. If the purple-flowered plant is heterozygous for both traits, ...

Name six specimen types that are often tested in forensic

Name six specimen types that are often tested in forensic toxicology; e.g. blood. Under what circumstances is each specimen preferred? Methadone is used to help drug addicts break the cycle. How does methadone work and i ...

Lab reportthe purpose of a biology lab report is to

Lab Report The purpose of a Biology lab report is to describe and analyze a laboratory experiment that explores a scientific concept so that other scientists might be able to replicate the experiment and investigate the ...

How do energy and nutrients move through ecosystems

How do energy and nutrients move through ecosystems? Indicate whether each is recycled. Define trophic levels and explain their involvement/role in energy movement.

Discuss the concept of risk and diversification and

Discuss the concept of risk and diversification and highlight types of risk correlation within portfolio with more than one asset?

1 e coli is a shortened name for a bacterium that lives in

1. E coli is a shortened name for a bacterium that lives in our gut. According to the rules of binomial nomenclature it is properly written as _______________. a. Escherichia COLI b. Escherichia Coli c. Escherichia coli ...

  • 4,153,160 Questions Asked
  • 13,132 Experts
  • 2,558,936 Questions Answered

Ask Experts for help!!

Looking for Assignment Help?

Start excelling in your Courses, Get help with Assignment

Write us your full requirement for evaluation and you will receive response within 20 minutes turnaround time.

Ask Now Help with Problems, Get a Best Answer

WalMart Identification of theory and critical discussion

Drawing on the prescribed text and/or relevant academic literature, produce a paper which discusses the nature of group

Section onea in an atwood machine suppose two objects of

SECTION ONE (a) In an Atwood Machine, suppose two objects of unequal mass are hung vertically over a frictionless

Part 1you work in hr for a company that operates a factory

Part 1: You work in HR for a company that operates a factory manufacturing fiberglass. There are several hundred empl

Details on advanced accounting paperthis paper is intended

DETAILS ON ADVANCED ACCOUNTING PAPER This paper is intended for students to apply the theoretical knowledge around ac

Create a provider database and related reports and queries

Create a provider database and related reports and queries to capture contact information for potential PC component pro