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One major adaptation to endurance training is the two-fold increase in mitochondrial volume. Why/how is having a greater mitochondrial volume advantageous in terms of substrate utilization (be specific)? Include in your answer an explanation of the graph below. Include any signal transduction mechanisms for an increase in mitochondrial volume density (sketch a figure to represent these mechanisms and associated factors and upregulated genes) . Are the greater mitochondria different functionally? Does training adaptations result in "better" mitochondria? Explain. Rate of Mitochondrial oxygen consumption ATP/ADP ratio Trained Untrained.

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