Question: List the different hypothalamic regions and peripheral signals involved in the control of feeding and satiety. Based on this information and how insulin acts in central nervous system and the periphery, would you expect people with Type 1 diabetes mellitus to have low body weight ("skinny") or high body weight ("overweight" or "obese")? Why? How about people with Type 2 diabetes mellitus? Why? Are the risks of neurological and other complications higher in Type 1 or Type 2 diabetes? Why?
Question: Describe the mechanisms by which input from GABAergic inhibitory neurons reduce action potential firing and neurotransmitter release. Why is the position of the inhibitory synapse on the neuron important in determining the effectiveness of the inhibitory stimuli?