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Lipid-soluble signaling molecules, such as testosterone, cross the membranes of all cells but affect only target cells because

Lipid-soluble signaling molecules, such as testosterone, cross the membranes of all cells but affect only target cells because

only target cells retain the appropriate DNA segments.
most cells lack the Y chromosome required.
only target cells possess the cytosolic enzymes that transduce the testosterone.
only in target cells is testosterone able to initiate the phosphorylation cascade leading to activated transcription factor.
intracellular receptors are present only in target cells.

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