A. Why is homologous recombination between nonsister chromatids preferred?

B.Is it possible to tell whether a DNA gap was generated during a homologous recombination eent that occurs at a heterozygous locus? Why or why not?

C. Based on its structure, explain how the synaptonemal complex could actually represent an obstacle to recombination.

D. Why is it important that resolvases function as symmetrical molecules with two active sites?

E. Explain why either a single- or double-strand break can result in a change in supercoiling.

F. The Cre/lox system is used to extensively to create "conditional knockouts" in mice, for example to delete a gene of interest in a particular tissue type. Describe how such a system might work.