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In this course, we have been learning how to demonstrate the involvement and requirement of a protein in a signaling pathway, which often requires specific modulation of the protein.

You can inhibit the function of a gene's products by which of the following approaches:

You may choose more than one answer. Explain your answers.

a) Knock out organism (where the gene has been removed from a transgenic organism)

b. RNAi specific for the genes RNA product

c. blocking antibody directed against the gene's product

d. antagonist drug to the gene's protein product

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