In human gut microbiome, it is proposed that the most inner layer of bacterial cells (most close to the epithelial cells) is composed of micro-aerobes. These bacteria grow relatively faster and harvest energy from diet better than strict anaerobes in the gut. Could you speculate certain unique features of those micro-aerobes in energy generation and cell metabolism?
It has been shown in different biofilm-forming bacteria that secreted small molecules and proteins can trigger biofilm disassembly and cell dispersal in late stages during biofilm development. Can you provide two such examples and discuss with molecular details how disassembly and dispersal occur? (Please read extra references if necessary)
Protein dynamics (accumulation and localization) plays a key role in Caulobacter crescentus development. Cell cycle control in C. crescentus is composed of four key regulatory proteins. Please provide two examples to explain why protein dynamics is critical for C. crescentus cell differentiation.