(Answered) In class we discussed how h146 of the beta-chain of normal

Academics

In class, we discussed how H146 of the β-chain of normal adult hemoglobin ends up in close proximity to D94 on the same chain when oxygen is delivered to the tissues. In hemoglobin Hiroshima, however, H146 on the β-chain has been changed to a D through mutation.

a) What effect, if any, does this mutation have on oxygen binding by hemoglobin Hiroshima, compared to normal hemoglobin? Explain. Hb Hiroshima will bind O2 easier. (You explain why).

b) What effect, if any, does this mutation have on the Bohr Effect of this mutant hemoglobin? Explain. This mutation will weaken the H+ portion of the Bohr effect, but will have no consequence on the CO2 portion of the Bohr Effect. (You explain why for both).

View complete question

Biology, Academics

Category:- Biology
Reference No.:- M92218444
Price:- $20

Verified Expert

Priced at $40 Now at $20, Verified Solution

Have any Question?Write your Review or question?

Related Questions in Biology

Calculate the concentrations at eqbm of h2co3 hco3- co32-

Calculate the concentrations at eqbm of H2CO3, HCO3-, CO32-, and H+ in a saturated aq solution of H2CO3 in which the original concentration of H2CO3 is 0.034M (Ka1= 4.3*10^-7, Ka2 = 4.8*10^-11)

Question phytoplankton chemosynthesis and mitochondriafor

Question: "Phytoplankton, Chemosynthesis, and Mitochondria" For your primary post, please respond to one of the following three topics with a post of at least 125 words that addresses each point given in the instructions ...

1 is a vitamin that sunlight on the skin typically

1. __________ is a vitamin that sunlight on the skin typically triggers within the body. 2. The specific cell type that produces bone tissue is called _____________. 3. The four components of a negative feedback loop ___ ...

If someone has been sitting without standing for 6 hours

If someone has been sitting without standing for 6 hours, and blood has been pooling in their veins, why would they feel dizzy when they stood up? How does this related to stroke volume and mean arterial pressure?

What did you determine was the relationship between surface

What did you determine was the relationship between surface tension and the polarity of the liquids you tested?

A filamentous organism has been isolated from decomposing

A filamentous organism has been isolated from decomposing organic matter. This organism has a cell wall but no chloroplast. why would you classify this organism into "domain eukarya, kingdom of fungi"

If the atomic number of an element is 12 and the atomic

If the atomic number of an element is 12 and the atomic mass is 25. How many protons are there in the nucleus? How many neutrons are there in the nucleus? How many electrons are in the atom?

Question choose one of the following topics and write a

Question: Choose one of the following topics and write a 400-500 word essay. You must cite at least 2 primary sources. Follow the proper citation format for articles and or websites. You must use direct (primary) sources ...

Experiment 1 symmetry in common objectsreview the objects

Experiment 1: Symmetry in Common Objects Review the objects listed below (many of which can be found in your lab kit). Decide what type of symmetry they possess. Explain why you chose the type of symmetry you did. 1. Saf ...

The ch50 assay is a traditional clinical assay that

The CH50 assay is a traditional clinical assay that measures the function of complement components. In a CH50 assay patient blood is drawn and serum separated from it (serum has no cells). Patient serum is mixed with ant ...

4,153,160 Questions Asked
13,132 Experts
2,558,936 Questions Answered

Ask Experts for help!!

Looking for Assignment Help?

Start excelling in your Courses, Get help with Assignment

Write us your full requirement for evaluation and you will receive response within 20 minutes turnaround time.

Ask Now Help with Problems, Get a Best Answer

Recent Questions

Ask Biology Expert