Question: If two parents are heterozygous carriers of Cystic Fibrosis, show a pedigree with four children showing the incidence of carriers and afflicted children. If each unafflicted child (carrier or not) has a 1 out of 30 chance of mating with another carrier of CF, what is the expected incidence CF disease in the third generation (frequency of CF in the grandchildren of the original couple)?
Question: Why might different ethnic populations differ in the ability of the genetic test to identify carriers of CF?